CKM Syndrome, a Newly Identified Disorder, Raises Heart Attack Risk


The American Heart Association (AHA) has identified a new medical condition to describe a mix of related health issues — cardiovascular disease, kidney disease, type 2 diabetes, and obesity — that can develop at the same time and increase the risks of heart attacks and strokes.

Awareness of this new condition, called cardiovascular-kidney-metabolic (CKM) syndrome, may help physicians recognize individuals who are at high risk for dying from heart disease at younger ages. In addition to considering the effects of cardiovascular disease (“C”) and kidney disease (“K”), this disorder factors in the impact of type 2 diabetes and obesity, known as metabolic conditions (“M”).

CKM syndrome prevention and treatment earlier in life may do the most to stave off serious health complications later, the AHA said in an advisory published in Circulation.

“The advisory addresses the connections among these conditions with a particular focus on identifying people at early stages of CKM syndrome,” said Chiadi Ndumele, MD, PhD, lead author of the advisory and an associate professor of medicine at Johns Hopkins University in Baltimore, in a statement. “Screening for kidney and metabolic disease will help us start protective therapies earlier to most effectively prevent heart disease and best manage existing heart disease.”


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